产品详情 |
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Antigenic Specificity | GRAF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GRAF Polyclonal Antibody. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | n/a |
Other Names | FLJ42530, GRAF, KIAA0621, OPHN1L, OPHN1L1 |
Gene, Accession # | Entrez: 23092; Uniprot: Q9UNA1 |
Catalog # | A304-340A |
Price | |
Order / More Info | GRAF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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