产品详情 |
Edit |   |
Antigenic Specificity | GRAF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GRAF Polyclonal Antibody. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | n/a |
Other Names | GRAF, GRAF1, OPHN1L, OPHN1L1, GTPase regulator associated with focal adhesion kinase pp125(FAK), oligophrenin-1-like protein, rho GTPase-activating protein 26 |
Gene, Accession # | Entrez: 23092, 71302; Uniprot: Q6ZQ82, Q9UNA1 |
Catalog # | PA5-28703 |
Price | |
Order / More Info | GRAF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|