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Antigenic Specificity | LRRTM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LRRTM2 Polyclonal Antibody. The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critica |
Immunogen | n/a |
Other Names | leucine-rich repeat neuronal 2 protein; leucine-rich repeat transmembrane neuronal 2 protein; leucine-rich repeat transmembrane neuronal protein 2 |
Gene, Accession # | Entrez: 107065, 26045, 685472; Uniprot: D4A7P2, O43300, Q8BGA3 |
Catalog # | PA5-21097 |
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Order / More Info | LRRTM2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27623146 |
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