| 产品详情 |
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| Antigenic Specificity | RhoB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RhoB Polyclonal Antibody. RhoB (Rho-related GTP-binding protein) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor - deletion of RhoB causes tumor formation. |
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| Immunogen | n/a |
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| Other Names | ARH6, ARHB, MST081, MSTP081, RHOH6, RHOB, oncogene RHO H6, rho cDNA clone 6, h6, Aplysia RAS-related homolog 6, rho-related GTP-binding protein RhoB, ras homolog gene family, member B |
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| Gene, Accession # | Entrez: 11852, 388, 64373; Uniprot: P62745, P62746, P62747 |
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| Catalog # | PA5-77865 |
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| Price | |
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| Order / More Info | RhoB Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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