| 产品详情 |
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| Antigenic Specificity | CD135 (Flt3) |
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| Clone | A2F10 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | PE-Cyanine5 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD135 (Flt3) Monoclonal Antibody (A2F10), PE-Cyanine5, eBioscience™. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differen |
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| Immunogen | n/a |
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| Other Names | RP11-153M24.3, CD135, FLK2, STK1 |
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| Gene, Accession # | Entrez: 14255; Uniprot: Q00342 |
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| Catalog # | 15-1351-82 |
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| Order / More Info | CD135 (Flt3) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19887396, 21731674, 23667053, 24451543, 26051918, 27365425, 27976999, 28004388, 28024152 |
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