| 产品详情 |
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| Antigenic Specificity | Phospho-HDAC1 (Ser421, Ser423) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-HDAC1 (Ser421, Ser423) Polyclonal Antibody. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases. |
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| Immunogen | n/a |
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| Other Names | Histone deacetylase 1, HD1, RPD3L1 |
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| Gene, Accession # | Entrez: 297893, 3065, 433759; Uniprot: O09106, Q13547, Q4QQW4 |
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| Catalog # | PA5-36911 |
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| Price | |
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| Order / More Info | Phospho-HDAC1 (Ser421, Ser423) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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