| 产品详情 |
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| Antigenic Specificity | MRGPRX2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 2-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MRGPRX2 Polyclonal Antibody. Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion. |
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| Immunogen | n/a |
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| Other Names | MRGPRX2, MRGX2, MAS-related GPR, member X2 |
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| Gene, Accession # | Entrez: 117194; Uniprot: Q96LB1 |
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| Catalog # | PA5-33951 |
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| Price | |
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| Order / More Info | MRGPRX2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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