产品详情 |
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Antigenic Specificity | MRGPRX1/MRGPRX3/MRGPRX4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | lyophilized |
Applications | Immunohistochemistry: 1:300-1:2000, Western Blot: 1:300-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MRGPRX1/MRGPRX3/MRGPRX4 Polyclonal Antibody. Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. |
Immunogen | n/a |
Other Names | Mas-related G-protein coupled receptor member X1, X3, X4; Sensory neuron-specific G-protein coupled receptor 3/4, MRGX1, SNSR3, SNSR4, GPCR, MAS-relat |
Gene, Accession # | Entrez: 117195, 117196, 259249; Uniprot: Q96LA9, Q96LB0, Q96LB2 |
Catalog # | OSR00109W |
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Order / More Info | MRGPRX1/MRGPRX3/MRGPRX4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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