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Antigenic Specificity | EphB4 |
Clone | 3D7G8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Immunocytochemistry: 3-5 µg/mL, Immunofluorescence: 3-5 µg/mL, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EphB4 Monoclonal Antibody (3D7G8). Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular |
Immunogen | n/a |
Other Names | HTK, MYK1, TYRO11, ephrin receptor EphB4, ephrin type-B receptor 4, hepatoma transmembrane kinase, soluble EPHB4 variant 1, soluble EPHB4 variant 2, soluble EPHB4 variant 3, tyrosine-protein kinase TYRO11, tyrosine-protein kinase receptor HTK |
Gene, Accession # | Entrez: 2050; Uniprot: P54760 |
Catalog # | 37-1800 |
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Order / More Info | EphB4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15722342, 16982731, 23579861, 26269757, 28165374 |
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