产品详情 |
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Antigenic Specificity | MAN1B1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAN1B1 Polyclonal Antibody. Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2. Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544]. Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699]. Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309]. |
Immunogen | n/a |
Other Names | Endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase, EC=3.2.1.113, ER alpha-1, 2-mannosidase |
Gene, Accession # | Entrez: 11253, 227619; Uniprot: A2AJ15, Q9UKM7 |
Catalog # | PA5-50029 |
Price | |
Order / More Info | MAN1B1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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