| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | LGR5 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 50 ug |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 5 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | LGR5 Polyclonal Antibody. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. |
|---|
| Immunogen | n/a |
|---|
| Other Names | LGR5, FEX, G-protein coupled receptor 49, G protein-coupled receptor 49, GPR67, GRP49, GPR49, HG38, G-protein coupled receptor 67 |
|---|
| Gene, Accession # | Entrez: 8549; Uniprot: O75473 |
|---|
| Catalog # | PA5-33728 |
|---|
| Price | |
|---|
| Order / More Info | LGR5 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|