产品名称 LGR5 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-33728
产品价格 现货询价,电话:010-67529703
产品规格 50 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityLGR5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size50 ug
Concentrationn/a
ApplicationsImmunohistochemistry (Paraffin): 5 µg/mL
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DescriptionLGR5 Polyclonal Antibody. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
Immunogenn/a
Other NamesLGR5, FEX, G-protein coupled receptor 49, G protein-coupled receptor 49, GPR67, GRP49, GPR49, HG38, G-protein coupled receptor 67
Gene, Accession #Entrez: 8549; Uniprot: O75473
Catalog #PA5-33728
Price
Order / More InfoLGR5 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料