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Antigenic Specificity | CD45 |
Clone | YKIX716.13 |
Host Species | Rat |
Reactive Species | canine |
Isotype | IgG2b, kappa |
Format | fluorescein (FITC) conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Monoclonal Antibody (YKIX716.13), FITC, eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restrict |
Immunogen | n/a |
Other Names | Cluster designation 45, common leukocyte antigen, T220 and B220 |
Gene, Accession # | Entrez: 490255 |
Catalog # | 11-5450-42 |
Price | |
Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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