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Antigenic Specificity | CD45.1 |
Clone | A20 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45.1 Monoclonal Antibody (A20), eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on ce |
Immunogen | n/a |
Other Names | CD45, L-CA, Lca, RT7, T200 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 14-0453-85 |
Price | |
Order / More Info | CD45.1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16754858, 17509906, 17548521, 18270249, 18453598, 18838544, 19047439, 19139082, 19384870, 19412181, 19478044, 19625643, 19797526, 19834548, 19864607, 19920180, 19949102, 20194813, 20197553, 20333625, 20348239, 21048154, 21245575, 21336280, 21402889, 21478403, 21483862, 21659540, 21873195, 22042976, 22151973, 22355330, 22547652, 22683125, 22802622, 22821961, 22902830, 22936656, 23221338, 23272202, 23334789, 23414756, 23434824, 23543755, 23603793, 23717671, 23749299, 23795291, 23826287, 23918988, 23933258, 23933982, 23977376, 24039598, 24168764, 24189163, 24297994, 24302580, 24487275, 24489086, 24613975, 24713170, 24736544, 24799116, 24859451, 25225459, 25245760, 25252912, 25348934, 25404365, 25487151, 25575242, 25692908, 25857745, 25957682, 25964370, 25981357, 26026061, 26107264, 26242630, 26311905, 26404698, 26440518, 26647186, 26682984, 26692174, 26773039, 26802627, 26830231, 26851219, 26944927, 27030824, 27180651, 27453007, 27523608, 27881740, 28487311, 28589939 |
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