| 产品详情 |
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| Antigenic Specificity | CD45 |
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| Clone | YW62.3 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 250 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:50-1:200, Immunofluorescence: Assay dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Description | CD45 Monoclonal Antibody (YW62.3). CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between differen |
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| Immunogen | n/a |
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| Other Names | B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, protein tyrosine phosphatase, receptor type, c polypeptide, receptor-type tyrosine-protein phosphatase C |
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| Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
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| Catalog # | MA1-81247 |
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| Price | |
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| Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11756193, 14976038, 16278309, 16365392, 23554495, 25886256 |
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