| 产品详情 |
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| Antigenic Specificity | p300 |
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| Clone | RW105 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, mustelid, nonhuman primate, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 200 µL |
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| Concentration | n/a |
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| Applications | ChIP assay: Assay-Dependent, Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunomicroscopy: Assay-Dependent, Immunoprecipitation: 1:10-1:500, Western Blot: 1:250-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p300 Monoclonal Antibody (RW105). p300 is a relatively stable, ubiquitously expressed, nuclear phosphoprotein which is conserved among a variety of mammalian species. It is actively synthesized and phosphorylated in both quiescent and proliferating cells. Cyclic AMP-responsive enhancer binding protein (CREB) binding protein (CBP) and p300 are closely related transcriptional coactivators and have been shown to directly interact with many different DNA-binding transcription factors including nuclear hormone receptors, CREB, c-Fos, C-Jun/v-Jun, c-Myb/v-Myb, TFIIB and MyoD. Both CBP and p300 have been shown to display histone acetyltransferase (HAT) activity, capable of acetylating all four core histone particles in nucleosomes. As a result of |
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| Immunogen | n/a |
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| Other Names | CREBBP/EP300 inhibitory protein 1, Cyclic AMP responsive enhancer binding protein, EP300: E1A binding protein p300, RB and P300 binding protein EID 1, |
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| Gene, Accession # | Entrez: 170915, 2033, 328572; Uniprot: B2RWS6, Q09472 |
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| Catalog # | MA1-16622 |
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| Price | |
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| Order / More Info | p300 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24619423, 28113136 |
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