产品详情 |
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Antigenic Specificity | p300 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | ChIP assay: 1:100, Immunoprecipitation: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | p300 Monoclonal Antibody, Biotin. EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. |
Immunogen | n/a |
Other Names | p300, KAT3B, EP300 |
Gene, Accession # | Entrez: 2033, 328572; Uniprot: B2RWS6, Q09472 |
Catalog # | 730044 |
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Order / More Info | p300 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 26121405 |
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