Edit |   |
Antigenic Specificity | KISS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1:25, Immunofluorescence: 1:25, Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KISS1 Polyclonal Antibody. This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third po |
Immunogen | n/a |
Other Names | Metastasis-suppressor KiSS-1; Kisspeptin-1; Metastin; Kisspeptin-54; Kisspeptin-14; Kisspeptin-13; Kisspeptin-10; KISS1 |
Gene, Accession # | Entrez: 3814; Uniprot: Q15726 |
Catalog # | PA5-72252 |
Price | |
Order / More Info | KISS1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |