| 产品详情 |
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| Antigenic Specificity | Ku80 |
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| Clone | 111 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 1:20-1:200, Immunofluorescence: 1:20-1:200, Immunoprecipitation: 2 µg/mL, Western Blot: 0.5-1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ku80 Monoclonal Antibody (111). The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. |
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| Immunogen | n/a |
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| Other Names | 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, Ku autoantigen, 80kDa, Ku86 autoantigen related protein 1,TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kD), X-ray repair cross-complementing protein 5, X-ray repair, complementing defective, repair in Chinese hamster, lupus |
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| Gene, Accession # | Entrez: 22596, 7520; Uniprot: P13010, P27641 |
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| Catalog # | MA5-12933 |
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| Price | |
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| Order / More Info | Ku80 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10075997, 10330147, 10360174, 10400681, 10854421, 10945984, 11821378, 11955432, 12527196, 12547193, 12917393, 14576316, 15385961, 15498778, 15718417, 15832367, 16309973, 17617645, 17720816, 18279852, 18355052, 18377429, 19759212, 19833092, 21188139, 21576354, 22226916, 23302228, 23337116, 23775790, 23868020, 23897892, 24340093, 24790221, 25582113, 26337656, 27111890, 28176781 |
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