| 产品详情 |
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| Antigenic Specificity | Ku80 |
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| Clone | SP130 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:25 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ku80 Monoclonal Antibody (SP130). X-ray repair cross-complementing protein 5 (XRCC5), alternative name (Ku80), is single stranded DNA-dependent ATP-dependent helicase. It involves in chromosome translocation. Ku80 along with Ku70 forms a heterodimeric protein originally identified as autoantigens associated with several autoimmune diseases including scleroderma, polymyositis and systemic lupus erythematosus. Ku is widely expressed nuclear protein that binds to and stabilizes the ends of DNA at telomeres or double-stranded DNA breaks. The inhibition of Ku80 can damage the DNA repair pathway of tumor cells and potentially increase the killing of cancer cells, and reduce drug resistance. |
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| Immunogen | n/a |
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| Other Names | KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, Ku autoantigen, 80kDa, Ku86 autoantigen related protein 1, TLAA, X-ray |
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| Gene, Accession # | Entrez: 7520; Uniprot: P13010 |
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| Catalog # | MA5-16375 |
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| Price | |
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| Order / More Info | Ku80 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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