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| Product Name | Recombinant Influenza A virus Polymerase acidic protein (PA), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 18.6kDa. Partial: 124-247aa. N-terminal 6xHis-tagged. Influenza A virus (strain A/x-31 H3N2). Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | RNA-directed RNA polymerase subunit P2 |
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| Gene, Accession, CAS # | PA, UniProt: Q9IQ47 |
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| Catalog # | RPC23675 |
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| Order / More Info | Recombinant Influenza A virus Polymerase acidic protein (PA), partial from BIOMATIK |
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| Product Specific References | n/a |
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