| 产品详情 |
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| Antigenic Specificity | Cyclin D1 |
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| Clone | CD1.1 |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Flow Cytometry: 2-8 µg/mL, Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Frozen): 2 µg/mL, Immunohistochemistry (Paraffin): Assay Dependent, Immunoprecipitation: 1 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin D1 Monoclonal Antibody (CD1.1). Cyclin D1 (PRAD-1, bcl-1) is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. Cyclin D1 is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL). In addition, cyclin D1 positively regulates protein phosphorylation, mammary gland epithelial cell proliferation, and fat cell differentiation. In humans, the CCND1 gene encoding cyclin D1 is present on chromosome 11. Cyclin D1 is a cytoplasmic and nuclear protein that is synthesized during G1 phase and assembles with either cyclin-dependent kinase 4 (CDK4) or CDK6 in response to growth factor stimulation. D-type cyclin-CDK c |
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| Immunogen | n/a |
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| Other Names | BCL1, D11S287E, PRAD1, U21B31, B-cell CLL/lymphoma 1, B-cell lymphoma 1 protein, BCL-1 oncogene, G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene |
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| Gene, Accession # | Entrez: 58919, 595; Uniprot: P24385, P39948 |
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| Catalog # | MA1-10324 |
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| Price | |
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| Order / More Info | Cyclin D1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25822340 |
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