| 产品详情 |
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| Antigenic Specificity | BDNF |
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| Clone | polyclonal |
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| Host Species | Sheep |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | lyophilized |
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| Applications | ELISA: 1:200-1:2000, Immunohistochemistry: 1:200-1:2000, Inhibition Assays: 1:10-1:50, Western Blot: 1:200-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BDNF Polyclonal Antibody. BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Although further processing generates the mature, 14 kDa protein, pro-BDNF is biologically active and is secreted in synaptic vesicles along with the mature form. BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons. Signaling occurs mainly through the tyrosine kinase receptor TrkB, although binding to the lower-affinity receptor, p75-NTR, has also been demonstrated. BDNF promotes neuronal survival and differentiation and has been shown to play a critical role in memory formation and synapti |
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| Immunogen | n/a |
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| Other Names | Brain-derived neurotrophic factor, Abrineurin |
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| Gene, Accession # | Entrez: 12064, 24225, 627; Uniprot: P21237, P23363, P23560 |
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| Catalog # | PA1-18364 |
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| Price | |
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| Order / More Info | BDNF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 20966022 |
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| 产品资料 |
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