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| Antigenic Specificity | Beclin 1 |
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| Clone | 2A4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:200 - 1:400, Immunohistochemistry: 1:200 - 1:1000, Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Beclin 1 Monoclonal Antibody (2A4). Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense. |
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| Immunogen | n/a |
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| Other Names | ATG6, VPS30, beclin1, ATG6 autophagy related 6 homolog; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin-1; coiled-coil myosin-like BCL2-interacting protein |
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| Gene, Accession # | Entrez: 8678; Uniprot: Q14457 |
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| Catalog # | MA5-15825 |
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| Price | |
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| Order / More Info | Beclin 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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