产品详情 |
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Antigenic Specificity | Beclin 1 |
Clone | OTI1F1 |
Host Species | Mouse |
Reactive Species | canine, human, rat |
Isotype | IgG2a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Beclin 1 Monoclonal Antibody (OTI1F1). Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense. |
Immunogen | n/a |
Other Names | ATG6, VPS30, beclin1, ATG6 autophagy related 6 homolog; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin-1; coiled-coil myosin-like BCL2-interacting protein |
Gene, Accession # | Entrez: 114558, 480513, 8678; Uniprot: Q14457, Q91XJ1 |
Catalog # | MA5-25480 |
Price | |
Order / More Info | Beclin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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