| 产品详情 |
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| Antigenic Specificity | RBCK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 2-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RBCK1 Polyclonal Antibody. E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination. Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome. Component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the L |
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| Immunogen | n/a |
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| Other Names | RanBP-type and C3HC4-type zinc finger-containing protein 1; Ubiquitin-conjugating enzyme 7-interacting protein 3; Hepatitis B virus X-associated protein 4; HBV-associated factor 4; RING finger protein 54; |
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| Gene, Accession # | Entrez: 10616, 24105; Uniprot: Q9BYM8, Q9WUB0 |
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| Catalog # | PA5-73012 |
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| Price | |
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| Order / More Info | RBCK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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