| 产品详情 |
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| Antigenic Specificity | MTA3 |
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| Clone | OTI2B8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MTA3 Monoclonal Antibody (OTI2B8). Metastasis-associated protein 3 (MTA3) is a subunit of the Mi-2/NuRD transcriptional corepressor complex. MTA3 and the Mi-2/NuRD complex mediate repression of Snail in breast cancer cells where MTA3 works to maintain a differentiated, epithelial status. The protein is involved in gene expression regulation by covalent modifications of histone proteins. There are two known isoforms of MTA3, a short and a long form. The short isoform binds to ER and sequesters it to the cytoplasm and betters non-genomic responses, whereas the long form is found in the nucleus. MTA3 is widely expressed in with highest expression in brain, adrenal glands, ovaries and virgin mammary glands. It has been found to be expressed in |
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| Immunogen | n/a |
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| Other Names | metastasis associated family, member 3, metastasis associated gene family, member 3, metastasis-associated protein MTA3 |
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| Gene, Accession # | Entrez: 57504; Uniprot: Q9BTC8 |
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| Catalog # | MA5-27203 |
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| Price | |
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| Order / More Info | MTA3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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