| 产品详情 |
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| Antigenic Specificity | RPE65 |
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| Clone | 401.8B11.3D9 |
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| Host Species | Mouse |
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| Reactive Species | bovine, canine, chicken, human, mouse, porcine, rat, Xenopus laevis |
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| Isotype | IgG1, kappa |
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| Format | biotin conjugate |
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| Size | 200 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:10-1:500, Immunofluorescence: 1:10-1:500, Immunohistochemistry (Frozen): 1:250, Immunohistochemistry (Paraffin): 1:250, Western Blot: 1:5000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RPE65 Monoclonal Antibody (401.8B11.3D9), Biotin. Highly conserved among vertebrate species, RPE65 is a major protein of the retinal pigment epithelium (RPE). RPE65 is essential for the regeneration of rhodopsin in the visual cycle. Mutations in RPE65 are responsible for certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA). Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and the accumulation of retinyl esters in the RPE. |
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| Immunogen | n/a |
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| Other Names | LCA2, RP20, mRPE65, rd12, sRPE65, RBP-binding membrane protein, all-trans-retinyl-palmitate hydrolase, p63, retinal pigment epithelium-specific 65 kDa protein, retinitis pigmentosa 20 (autosomal recessive), retinoid isomerohydrolase, retinol isomerase |
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| Gene, Accession # | Entrez: 100516743, 19892, 282043, 395700, 403803, 6121, 89826; Uniprot: O70276, Q16518, Q28175, Q91ZQ5, Q9TVB8, Q9YGX2 |
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| Catalog # | MA5-16040 |
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| Price | |
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| Order / More Info | RPE65 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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