Edit |   |
Antigenic Specificity | SLC24A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | purified |
Size | 200 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Frozen): 1:100, Western Blot: 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SLC24A2 Polyclonal Antibody. Sodium/calcium-potassium exchanger proteins (NCKX1) have been reported to occur in retinal photoreceptors and in brain (NCKX2). Unlike the abundant and widely expressed sodium/calcium exchanger which catalyzes the exchange of 3 sodium ions for 1 calcium ion to modulate intracellular calcium levels, NCKX isoforms exchange 4 sodium ions for 1 calcium and 1 potassium ion. The sodium/calcium-potassium exchanger uses the transmembrane sodium gradient to catalyze countertransport of calcium in a potassium-dependent mechanism against its electrochemical gradient. It is hypothesized that NCKX2 plays a significant role in calcium homeostasis and the regulation of neuronal function. |
Immunogen | n/a |
Other Names | NCKX2 |
Gene, Accession # | Entrez: 84550; Uniprot: O54701 |
Catalog # | PA1-926 |
Price | |
Order / More Info | SLC24A2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 14684869 |