| 产品详情 |
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| Antigenic Specificity | Perlecan |
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| Clone | A7L6 |
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| Host Species | Rat |
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| Reactive Species | bovine, human, mouse, porcine |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:20 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Perlecan Monoclonal Antibody (A7L6). Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplast |
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| Immunogen | n/a |
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| Other Names | HSPG, basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), perlecan proteoglycan |
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| Gene, Accession # | Entrez: 100517288, 15530, 3339, 444872; Uniprot: P98160, Q05793 |
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| Catalog # | MA5-14641 |
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| Price | |
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| Order / More Info | Perlecan Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12591930, 16495570, 20434212, 21289070, 22297676, 24132234, 24149428, 27856617 |
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