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Antigenic Specificity | HARS2 |
Clone | OTI2D6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HARS2 Monoclonal Antibody (OTI2D6). Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene. |
Immunogen | n/a |
Other Names | Probable histidyl-tRNA synthetase, mitochondrial [Precursor]; EC 6.1.1.21; Histidine--tRNA ligase; HisRS; Histidine--tRNA ligase-like; HARS2; HARSL; HARSR; HO3 |
Gene, Accession # | Entrez: 23438; Uniprot: P49590 |
Catalog # | MA5-25744 |
Price | |
Order / More Info | HARS2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |