| 产品详情 |
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| Antigenic Specificity | PI4K2A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PI4K2A Polyclonal Antibody. Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs. PI4K II is activated by detergent and inhibited by adenosine. Overexpression of PI4KII in COS-7 cells increases synthesis of PtdIns4P. Some cells overexpressing PI4KII have scattered or no perinuclear Golgi. Knockdown of PI4KII by RNA interference (RNAi) does not disrupt the Golgi, and some cells show expanded Golgi. RNAi reduces the Golgi level of PtdIns4P and blocks the association between AP1 and the trans-Golgi network. PI4 |
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| Immunogen | n/a |
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| Other Names | Type II alpha phosphatidylinositol 4-kinase; Phosphatidylinositol 4-kinase type II |
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| Gene, Accession # | Entrez: 55361, 84095; Uniprot: Q2TBE6, Q9BTU6 |
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| Catalog # | PA5-15275 |
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| Price | |
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| Order / More Info | PI4K2A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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