| 产品详情 |
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| Antigenic Specificity | PIK3AP1 |
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| Clone | OTI6H6 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PIK3AP1 Monoclonal Antibody (OTI6H6). Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL. |
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| Immunogen | n/a |
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| Other Names | Pik3ap1, 1810044J04Rik, B cell adaptor protein, BCAPB-cell adapter for phosphoinositide 3-kinase, B-cell phosphoinositide 3-kinase adapter protein 1, FLJ35564, phosphoinositide 3-kinase adapter protein 1, phosphoinositide-3-kinase adaptor protein 1, RP11-34E5.3 |
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| Gene, Accession # | Entrez: 118788, 294048, 705017; Uniprot: Q6ZUJ8 |
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| Catalog # | MA5-25250 |
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| Price | |
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| Order / More Info | PIK3AP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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