产品详情 |
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Antigenic Specificity | CD264 (TRAIL-R4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 10 µg/mL, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD264 (TRAIL-R4) Polyclonal Antibody. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosi |
Immunogen | n/a |
Other Names | CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD, TRAIL receptor 4 |
Gene, Accession # | Entrez: 22035, 246775, 8743, 8793; Uniprot: P50591, P50592, Q9UBN6 |
Catalog # | PA5-19896 |
Price | |
Order / More Info | CD264 (TRAIL-R4) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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