| 产品详情 |
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| Antigenic Specificity | FEN1 |
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| Clone | OTI1F3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FEN1 Monoclonal Antibody (OTI1F3). The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by |
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| Immunogen | n/a |
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| Other Names | FEN-1, MF1, RAD2, DNase IV, flap endonuclease 1, hFEN-1, maturation factor 1, maturation factor-1 |
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| Gene, Accession # | Entrez: 2237; Uniprot: P39748 |
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| Catalog # | MA5-26550 |
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| Price | |
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| Order / More Info | FEN1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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