| 产品详情 |
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| Antigenic Specificity | PIKE |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PIKE Polyclonal Antibody. AGAP2 (also known as PIKE-A), a putative oncogene, shows elevated expression in cancer cells compared to non-transformed cells and has been implicated as regulators of cancer cell invasion into normal tissues. A contributor to brain, eye, breast and liver cancers, AGAP2 belongs to the centaurin gamma-like family with two ANK repeats, an Arf-GAP domain, a Miro domain and a PH domain is a GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. The Arf-GAP domain interacts with G domain and may regulate its GTPase activity. GAP activity of AGAP2 is stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and, to a lesser extent, by phosphatidylinositol 3,4,5-trisphosphate (PIP3). |
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| Immunogen | n/a |
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| Other Names | CENTG1; centaurin, gamma 1; AGAP2; FLJ16430; GGAP2; KIAA0167; PIKE; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; GTP-binding and GTPase activating protein 2; centaurin gamma1; phosphoinositide 3-kinase enhancer |
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| Gene, Accession # | Entrez: 116986; Uniprot: Q99490 |
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| Catalog # | A304-263A-T |
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| Price | |
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| Order / More Info | PIKE Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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