产品详情 |
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Antigenic Specificity | SPDYA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SPDYA Polyclonal Antibody. Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, |
Immunogen | n/a |
Other Names | hSpy/Ringo A; MGC110856; MGC57218; OTTHUMP00000082662; OTTHUMP00000082663; OTTHUMP00000082664; Rapid inducer of G2/M progression in oocytes A; RINGO A; RINGO3; SPDY1; Speedy A; Speedy homolog 1 (Drosophila); Speedy homolog A (Xenopus laevis); Speedy homolog A; Speedy-1; SPY1; |
Gene, Accession # | Entrez: 192209, 245711, 70891; Uniprot: Q5IBH7, Q5MJ70, Q8R496 |
Catalog # | PA5-76080 |
Price | |
Order / More Info | SPDYA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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