| 产品详情 |
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| Antigenic Specificity | HAX1b |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HAX1b Polyclonal Antibody. The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. |
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| Immunogen | n/a |
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| Other Names | RP11-137P24.1, HCLSBP1, HS1BP1, SCN3; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1-associated protein X-1; HS1 binding protein; HS1-associating protein X-1; HS1-binding protein 1; HSP1BP-1 |
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| Gene, Accession # | Entrez: 10456, 23897, 291202; Uniprot: O00165, O35387, Q7TSE9 |
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| Catalog # | PA5-20650 |
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| Price | |
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| Order / More Info | HAX1b Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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