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Antigenic Specificity | CD11b |
Clone | M1/70.15 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | purified |
Size | 250 ug |
Concentration | n/a |
Applications | Flow Cytometry: 0.1 µg/1x10^6 cells, Functional Assay: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11b Monoclonal Antibody (M1/70.15). CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of |
Immunogen | n/a |
Other Names | CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M |
Gene, Accession # | Entrez: 16409; Uniprot: P05555 |
Catalog # | MA5-17857 |
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Order / More Info | CD11b Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10359586, 10447772, 10452982, 10515662, 10570285, 10611339, 10979970, 11067879, 11290552, 11698429, 11785670, 11971010, 12675196, 12731047, 12914754, 1398927, 14534083, 14734856, 14768057, 15034094, 15067047, 15122268, 15187137, 15494516, 15536638, 15558055, 15667568, 15784728, 15802308, 15857940, 15870020, 16365392, 16388484, 16703567, 16751424, 16943245, 1718880, 17304113, 17895395, 17911623, 18077084, 18594150, 18954266, 19201851, 19234155, 19570869, 19759906, 21211579, 21494554, 21515793, 22291907, 22529293, 23630952, 23643646, 24098126, 25231302, 25691593, 26463167, 26629403, 28300057, 81133, 8150225, 8541551, 8666936, 89034, 9040011, 9112373, 9531604, 9551995 |
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