产品详情 |
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Antigenic Specificity | WNK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | WNK1 Polyclonal Antibody. WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy. |
Immunogen | n/a |
Other Names | Serine/threonine-protein kinase WNK1 |
Gene, Accession # | Entrez: 116477, 232341, 65125; Uniprot: P83741, Q9H4A3, Q9JIH7 |
Catalog # | PA5-80229 |
Price | |
Order / More Info | WNK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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