产品详情 |
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Antigenic Specificity | MINA53 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MINA53 Polyclonal Antibody. MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias. |
Immunogen | n/a |
Other Names | MDIG, MINA53, NO52, MYC-induced nuclear antigen, mineral dust induced gene protein, mineral dust-induced gene protein, myc-induced nuclear antigen, 53 kDa, nucleolar protein 52 |
Gene, Accession # | Entrez: 84864; Uniprot: Q8IUF8 |
Catalog # | 40-9500 |
Price | |
Order / More Info | MINA53 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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