| 产品详情 |
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| Antigenic Specificity | Rhodopsin |
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| Clone | 1D4 |
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| Host Species | Mouse |
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| Reactive Species | bovine, human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:1,000, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100-1:1000, Immunoprecipitation: Assay dependent, Western Blot: 1:100-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rhodopsin Monoclonal Antibody (1D4). Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process of converting light to an electrochemical signal begins when the membrane-bound protein, rhodopsin, absorbs light within the retina. Photoexcitation of rhodopsin causes the cytoplasmic surface of the protein to become catalytically active. In the active state, rhodopsin activates transducin, a GTP binding protein. Once activated, transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE). The decrease of intracellular cGMP concentrations causes the ion channels within the outer segment of the rod or cone to close, thus causing |
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| Immunogen | n/a |
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| Other Names | Rho, OPN 2, Opsin 2, Retinitis Pigmentosa 4, RP 4 |
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| Gene, Accession # | Entrez: 212541, 24717, 509933, 6010; Uniprot: P02699, P08100, P15409, P51489 |
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| Catalog # | MA1-722 |
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| Price | |
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| Order / More Info | Rhodopsin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12874105, 14578424, 17215248, 17389522, 19023138, 19837033, 20552423, 21050919, 22292038, 2457026, 24943310, 27680706, 28045251, 9618546, 9843205 |
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