产品详情 |
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Antigenic Specificity | Grancalcin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Grancalcin Polyclonal Antibody. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. |
Immunogen | n/a |
Other Names | GCL, grancalcin, grancalcin, EF-hand calcium-binding protein, grancalcin, penta-EF-hand protein |
Gene, Accession # | Entrez: 25801; Uniprot: P28676 |
Catalog # | PA5-30497 |
Price | |
Order / More Info | Grancalcin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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