产品详情 |
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Antigenic Specificity | PTGIR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PTGIR Polyclonal Antibody. Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2α, PGI2, TXA2 and PGD2. These lipid mediators interact with specific members of G protein-coupled prostanoid receptors, designated EP, FP, IP, TP and DP, respectively. The IP Receptor binds prostacyclin, PGI2, the main prostanoid synthesized by vascular tissues. First discovered in 1976, prostacyclin is involved in platelet aggregation inhibition, vasodilatation and cytoprotection, and either prostacyclin or its analogs are used in the treatment of hypertension. Upon binding to the IP Receptor, prostacyclin activates adenylate cyclase primarily through the Gas protein. The gene encoding the human IP Receptor is located on chromoso |
Immunogen | n/a |
Other Names | Prostacyclin receptor; Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor; PTGIR; PRIPR |
Gene, Accession # | Entrez: 5739; Uniprot: P43119 |
Catalog # | PA5-75406 |
Price | |
Order / More Info | PTGIR Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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