| 产品详情 |
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| Antigenic Specificity | NAB2 |
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| Clone | OTI1E12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NAB2 Monoclonal Antibody (OTI1E12). Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2, are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 |
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| Immunogen | n/a |
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| Other Names | MADER, EGR-1-binding protein 2, EGR1 binding protein 2, NGFI-A-binding protein 2, melanoma-associated delayed early response protein |
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| Gene, Accession # | Entrez: 4665; Uniprot: Q15742 |
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| Catalog # | MA5-26644 |
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| Price | |
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| Order / More Info | NAB2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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