产品详情 |
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Antigenic Specificity | NAB2 |
Clone | OTI3H5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NAB2 Monoclonal Antibody (OTI3H5). Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2, are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 h |
Immunogen | n/a |
Other Names | MADER, EGR-1-binding protein 2, EGR1 binding protein 2, NGFI-A-binding protein 2, melanoma-associated delayed early response protein |
Gene, Accession # | Entrez: 4665; Uniprot: Q15742 |
Catalog # | MA5-26637 |
Price | |
Order / More Info | NAB2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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