产品详情 |
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Antigenic Specificity | GALE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GALE Polyclonal Antibody. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symp |
Immunogen | n/a |
Other Names | SDR1E1, UDP galactose-4'-epimerase, UDP-galactose 4-epimerase, UDP-glucose 4-epimerase, galactose-4-epimerase, UDP-, galactowaldenase, short chain dehydrogenase/reductase family 1E, member 1 |
Gene, Accession # | Entrez: 2582; Uniprot: Q14376 |
Catalog # | PA5-30037 |
Price | |
Order / More Info | GALE Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
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