产品详情 |
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Antigenic Specificity | GALE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, guinea pig, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GALE Polyclonal Antibody. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symp |
Immunogen | n/a |
Other Names | UDP-galactose-4-epimerase, SDR1E1 |
Gene, Accession # | Entrez: 100345092, 100621392, 100722082, 100855555, 114860, 2582, 523154, 74246; Uniprot: P18645, Q14376, Q8R059 |
Catalog # | PA5-44158 |
Price | |
Order / More Info | GALE Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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