| 产品详情 |
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| Antigenic Specificity | GALE |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:20-1:50, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GALE Polyclonal Antibody. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symp |
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| Immunogen | n/a |
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| Other Names | SDR1E1, UDP galactose-4'-epimerase, UDP-galactose 4-epimerase, UDP-glucose 4-epimerase, galactose-4-epimerase, UDP-, galactowaldenase, short chain dehydrogenase/reductase family 1E, member 1 |
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| Gene, Accession # | Entrez: 114860, 2582, 74246; Uniprot: P18645, Q14376, Q8R059 |
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| Catalog # | PA5-52423 |
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| Price | |
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| Order / More Info | GALE Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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