产品详情 |
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Antigenic Specificity | SMN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 20 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SMN1 Polyclonal Antibody. The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2. |
Immunogen | n/a |
Other Names | BCD541, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMN2, SMNT, T-BCD541, component of gems 1; gemin 1; gemin-1; survival motor neuron protein |
Gene, Accession # | Entrez: 6606; Uniprot: Q16637 |
Catalog # | A301-863A-T |
Price | |
Order / More Info | SMN1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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