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Antigenic Specificity | Smoothelin |
Clone | R4A |
Host Species | Mouse |
Reactive Species | canine, chicken, feline, human, nonhuman primate, porcine |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:100-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Smoothelin Monoclonal Antibody (R4A). Smoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC-like characteristics, such as myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle do not contain smoothelin. Confocal scanning laser microscopy of tissue sections, as well as transfection studies, show a filamentous organization of smoothelin that is different from that of desmin and vimentin. Smoothelin colocalizes with actin stress fibers. Two tissue specific |
Immunogen | n/a |
Other Names | SMSMO, SMTN |
Gene, Accession # | Entrez: 100858894, 101094884, 414369, 477542, 6525; Uniprot: P53814 |
Catalog # | OMA1-06020 |
Price | |
Order / More Info | Smoothelin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12388302 |
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